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| 品牌 | absin |
|---|
| 概述 | |
|---|---|
| 描述 | Ebselen is an interesting organoselenium compound displaying antiinflammatory and antioxidant properties. Ebselen is shown to inhibit the 5-lipoxygenase (5-LO) and 15-lipoxygenase (15-LO) enzymes in the absence of glutathione. Ebselen also inhibits Cox (cyclooxygenase), PKC (protein kinase C), DECR1 (NADPH), and Mox-1 (NADPH oxidase). The oxidation of low density lipoproteins by free radicals is suppressed by the antioxidant action of Ebselen. Ebselen is an inhibitor of Cox-1, Cox-2, NOS, GST and IDO. |
| 别名 | 2-Phenyl-1,2-benzisoselenazol-3(2H)-one; Harmokisane; Ebselene |
| 应用
| An inhibitor of 5-LO, 15-LO, Cox, NADPH, and NADPH oxidase |
| 性能 | |
|---|---|
| 保存方法 | Store at RT |
| 纯度 | ≥98% |
| 分子量 | 274.18 |
| 溶解性 | Soluble in PBS pH7.2, DMSO (25 mg/ml), ethanol (10 mg/ml), methanol, acetone, acetonitrile, and DMF (~5 mg/ml). |
| CAS号 | 60940-34-3 |
| 外观 | White solid |
| 功能 | inhibitor |
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