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| 品牌 | absin |
|---|
| 概述 | |
|---|---|
| 描述 | Gabapentin-lactam, a cell permeable compound, has been reported to reduce oxygen glucose deprivation-induced [3H]glutamate release in rat ischemia hippocampal slices. Glutamate has been an excitotoxin and its inhibition can decrease the number of surviving ganglion cells in vitro. In mechanistic studies it has been demonstrated that the neuroprotective characteristics of Gabapentin-lactam take effect via opening of ATP-sensitive potassium channels. |
| 别名 | β, β-pentamethylen-gamma-butyrolactam |
| 应用
| A potassium channel modulator and potential neuroprotector |
| 性能 | |
|---|---|
| 保存方法 | Store at RT |
| 纯度 | 99% |
| 分子量 | 153.2 |
| 溶解性 | Soluble in DMSO (>40 mg/ml), ethanol (>40 mg/ml), chloroform, dimethyl sulfoxide, DMF, methanol, and water (partly miscible). |
| CAS号 | 64744-50-9 |
| 外观 | white |
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