全国服务咨询热线:

Products产品中心
首页 > 产品中心 > 抗体 > 内参抗体 > abs132004Rabbit anti-GAPDH Polyclonal Antibody

Rabbit anti-GAPDH Polyclonal Antibody

简要描述:Rabbit anti-GAPDH Polyclonal Antibody的应用WB: 1:3000-1:30000, IHC: 1:200, IF: 1:200, ELISA(peptide): 1:20000-1:40000

  • 产品型号:abs132004
  • 厂商性质:生产厂家
  • 更新时间:2024-07-16
  • 访  问  量:1248

详细介绍

品牌absin货号abs132004
规格100ug供货周期现货
主要用途WB: 1:3000-1:30000, IHC: 1:200应用领域化工,生物产业,农业,制药,综合

公告提醒:AG8亚国服务所有产品和服务仅用于科学研究,也不为任何个人提供产品和服务!


截止2024年7月,该产品引用文献120+篇!!


名称:Rabbit anti-GAPDH Polyclonal Antibody

宿主:Rabbit

反应种属:Human, Mouse, Rat, Pig, Bovine, Goat, Monkey, Chicken

免疫原:A synthesized peptide derived from human GAPDH.

纯化方法:The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.


分子量:

Predicted molecular weight: 36kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.


背景说明:

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.


细胞定位:

Cytoskeleton;Cytosol;Extracellular region or secreted;Nucleus;Plasma Membrane;


产品咨询

留言框

  • 产品:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 省份:

  • 详细地址:

  • 补充说明:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7
AG8亚国服务(上海)生物科技有限公司
地址:上海市浦东新区新浩路58号申江科创园18栋
邮箱:wulan@absin.cn
传真:
关注我们
欢迎您关注我们的微信公众号了解更多信息:
欢迎您关注我们的微信公众号
了解更多信息