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PDGF-BB(10ug)

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  • 产品型号:abs04190
  • 厂商性质:生产厂家
  • 更新时间:2024-07-08
  • 访  问  量:1049

详细介绍

品牌absin货号abs04190
规格10ug供货周期一周
概述
描述Recombinant Human Plaet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed.
别名Plaet-Derived Growth Factor Subunit B, PDGF Subunit B, PDGF-2, Plaet-Derived Growth Factor B Chain, Plaet-Derived Growth Factor Beta Polypeptide, Proto-Oncogene c-Sis, Becaplermin, PDGFB, PDGF2, SIS
形态Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
来源E.coli
氨基酸序列MSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQ VQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVAAARPVT
内毒素水平Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Accession #P01127
性能
背景Plaet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Plaet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the plaet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by plaets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
纯度Greater than 95% as determined by reducing SDS-PAGE.

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